Origin Life

India’s First Dedicated Lab for Subfertile Couples ( निःसंतान दम्पत्तियों के लिए भारत की पहली और एकमात्र समर्पित लैब)

Female Tests

Male Tests

Therapeutic Solutions

STEP - Subfertility Test Endometrium Profile

Implantation is a multi-factorial process and endometrium is its rate-limiting factor. A complete endometrium profile can define the causes of implantation failure. The STEP test defines the role of endometrial factors responsible for infertility, recurrent implantation failure (RIF), recurrent pregnancy loss (RPL), and IVF failure. The STEP test assesses multiple endometrial factors at a time and results in a complete endometrial analysis.

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“Some reproductive failures are immunologically determined”.
To analyze the immune competency of the endometrium, the “Endo- Immune test” comprised of immune cells and cytokines described as active participants (uNK cells, Plasma Cells, Th1, Th17) in immunity-derived infertility. For implantation to occur, there must be a balance between pro-inflamma-tory and anti-inflammatory cytokines. “Endo-Immune test” allows the identification of implantation failure or recurrent miscarriage causes in the case where embryonic factors have been previously ruled out / normal.

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ERMA - Endometrium Receptivity
and Maturation Analysis

Implantation is a multi-factorial process and endometrium is its rate-limiting factor. A complete endometrium profile can define the causes of implantation failure. The STEP test defines the role of endometrial factors responsible for infertility, recurrent implantation failure (RIF), recurrent pregnancy loss (RPL), and IVF failure. The STEP test assesses multiple endometrial factors at a time and results in a complete endometrial analysis.

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Endometrial Infection Test (EIT)

“Infection and inflammation of the endometrium are hindering implantation.”
Infection in the endometrium poses a challenge to the implantation process as it incurs potential harm to the environment of the endometrium. The environment of endometrium required for attachment of embryo must be infection-free so that the implantation could occur. Various studies have shown women experiencing recurrent pregnancy losses (RPL) characterized by multiple miscarriages, recurrent implantation failure (RIF), and unexplained infertility often exhibit infection and inflammation in the endometrium.

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Semen Analysis

The Semen Analysis conducted by Origin LIFE aims to provide valuable insights into the reproductive health of males. This comprehensive analysis involves the examination of various parameters, including sperm count, motility (movement), morphology (shape and size of sperm), and other factors such as volume, pH, and liquefaction time. A thorough evaluation of these parameters helps in identifying potential issues that may contribute to infertility or reproductive challenges. By offering Semen Analysis services, Origin LIFE plays a crucial role in supporting individuals and couples in their journey towards understanding and addressing male fertility concerns.

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Sperm DNA Fragmentation

Origin LIFE Diagnostic Laboratory performs the Sperm DNA Fragmentation test, a specialized diagnostic procedure crucial for assessing DNA integrity within sperm cells and understanding potential male fertility issues. This test identifies breaks or abnormalities in sperm DNA structure, impacting fertility outcomes. The assessment gauges DNA damage levels, with excessive fragmentation adversely affecting fertilization and embryo development. Results offer insights into male infertility causes, recurrent pregnancy loss, or unsuccessful assisted reproductive treatments. Origin LIFE aims to enhance personalized fertility management, guiding healthcare professionals in tailored treatment plans, potentially involving lifestyle adjustments, antioxidant
therapies, or advanced reproductive technologies for increased chances of successful pregnancy. This commitment underscores Origin LIFE’s dedication to comprehensive reproductive health diagnostics, aiding individuals and couples in achieving their reproductive goals.

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PRP & PBMC Therapy

Platelet-rich plasma (PRP) and Peripheral blood mononuclear cell (PBMC) is an autologous proc-uct derived from the whole blood of the patient. Flushing of the uterus with PRP or PBMC prepares Endometrium for implantation. PRP and PBMC treatments represent one of the major breakthroughs in medical science over the last 15 years. These treatment options offer relief from a variety of diseases and their symptoms. We, at Origin LIFE offer PRP and PBMC therapy for Uterine Receptivity.
 

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Immune Therapy (LIT)

Immunotherapy (LIT) is a treatment for unexplained pregnancy loss or IVF failure and involves the modulation of the immune response. This is done by inducing certain immunological changes in the mother’s body, so that immunological rejection of the fetus is prevented in cases of RM, IVF failure. This cell therapy mechanism induces the production of cytokines & growth factors, blocking of antibodies, proliferation of B10 cells, reduction of NK cells activity, increase in Th2 and T-reg cells and decrease in Th1 and Th17 cells. Overall, LIT modulates the mother’s immune system to protect the fetus and make the pregnancy prosperous.

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